| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cd4c908be89b8b099811c8d31c82356b |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C17-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C45-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C303-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C29-14 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C45-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C309-65
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C25-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C303-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C33-46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C17-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C29-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C47-55 |
| filingDate |
2020-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e46f500c14d911cad6d991120ba6099c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_89255263bcedc250762afe5f9e1f1102 |
| publicationDate |
2021-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-112479941-A |
| titleOfInvention |
A kind of preparation method of 2-substituted-3-aryl halobenzyl derivatives |
| abstract |
The invention discloses a preparation method of a 2-substituted-3-aryl benzyl halide derivative, and belongs to the field of chemical synthesis. The method of the present invention comprises the following steps: a) using 2-substituted-3-hydroxybenzaldehyde as a raw material to prepare 2-substituted-3-formylphenol trifluoromethanesulfonate; b) using 2-substituted-3-formylphenol as a raw material Acylphenol triflate and arylboronic acid compounds are used as raw materials to prepare 2-substituted-3-arylbenzaldehyde; c) using 2-substituted-3-arylbenzaldehyde as raw material, to prepare 2-substituted-arylbenzaldehyde 3-arylbenzyl alcohol; d) using 2-substituted-3-arylbenzyl alcohol as a raw material to prepare the 2-substituted-3-aryl benzyl halide derivative shown in formula (I). |
| priorityDate |
2020-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |