http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112472708-B

Outgoing Links

Predicate Object
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7048
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7048
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-08
filingDate 2020-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2023-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2023-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-112472708-B
titleOfInvention Application of Eleutheroside E in the preparation of medicines for preventing and/or treating KOA
abstract The present invention relates to a new application of Eleutheroside E, in particular to the application of Eleutheroside E in the preparation of medicines for preventing and/or treating knee osteoarthritis (KOA) and a pharmaceutical composition for treating knee osteoarthritis (KOA). The pharmaceutical composition for treating knee osteoarthritis can be made into injections, tablets, capsules, granules, drops, granules or ointments by adding common pharmaceutical auxiliary components to Eleutheroside E with a purity of more than 98%. The results of pharmacological experiments show that Eleutheroside E can significantly improve inflammatory cell infiltration, fibrous tissue hyperplasia, and cartilage surface destruction in osteoarthritis sites, and reduce the levels of MMP‑3, MMP‑9 and PGE 2 in serum. Eleutheroside E has a strong anti-inflammatory effect. Role in knee osteoarthritis (KOA). Therefore, Eleutheroside E can be used to prepare medicines for preventing and/or treating KOA. The invention provides a new drug source for the treatment of KOA.
priorityDate 2020-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

Incoming Links

Predicate Subject
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100825041-B1
isDiscussedBy http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID2707
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID419491273
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID71312557
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID426371131

Total number of triples: 21.