http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112472671-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6931 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-555 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G81-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-282 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-61 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K33-243 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y40-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-555 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-282 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K33-243 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82Y40-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G81-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82Y5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-61 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-69 |
| filingDate | 2020-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112472671-B |
| titleOfInvention | Albumin/polysaccharide polymer based platinum nano prodrug and preparation method and application thereof |
| abstract | An albumin/polysaccharide polymer platinum nano prodrug and a preparation method and application thereof are disclosed, wherein 1- (3-dimethylaminopropyl) -3-ethylcarbodiimide hydrochloride is added into a polysaccharide polymer aqueous solution containing carboxyl to activate the carboxyl, a dibasic hydrazide is added after the reaction, and the reaction is continued for 12-72 hours to obtain a hydrazide polysaccharide polymer; preparing albumin, hydrazide polysaccharide polymer and 1, 4-butanediol diglycidyl ether into an aqueous solution, dropwise adding ethanol, and obtaining albumin/polysaccharide polymer nanoparticles after 1-24 hours after the dropwise adding; mixing the albumin/polysaccharide polymer suspension with a platinum anti-tumor drug solution to obtain the albumin/polysaccharide polymer based platinum nano prodrug. The nano carrier can be directly loaded without any chemical modification on the platinum anti-tumor drugs when the platinum anti-tumor drugs are loaded, and has the advantages of mild process conditions, short loading time, high loading efficiency and the like. |
| priorityDate | 2020-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 77.