http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112469990-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_215a1cadcfb8efd59b8ed523beea6279 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2021-6421 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-587 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0065 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6489 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-574 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00 |
filingDate | 2019-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9b1dbd3915a18a5f87ec1cbf67e0ffa3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_82db6c05c7919b7d3640b4324f345a5c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_71a172ca44106cda37cd16c80a9977c5 |
publicationDate | 2021-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-112469990-A |
titleOfInvention | Cancer cell detection and imaging systems, methods and products |
abstract | The present invention discloses a method of distinguishing cancerous and healthy cells of a subject from each other, said method comprising the steps of (i) contacting a tissue region of the subject suspected of containing at least some cancerous cells with a plurality of nanodiamonds, wherein the plurality of nanodiamonds comprises a first plurality of conjugates and a second plurality of conjugates, wherein conjugates in the first plurality of conjugates consist of a first nanodiamond and one or more cancer cell targeting agents, wherein the first nanodiamond has a first type of color center, the conjugates in the second plurality of conjugates consisting of a second nanodiamond and one or more healthy cell targeting agents, wherein the second nanodiamond has a second type of color center, and step (ii) applies light of a first wavelength to excite the first type of color center and applies light of a second wavelength to excite the second type of color center; wherein when the tissue region is contacted with the plurality of nanodiamonds, cancer cells are attached to the first plurality of conjugates and healthy cells are attached to the second plurality of conjugates; wherein when light is applied to the tissue region, the color centers of the nanodiamonds of the first plurality of conjugates attached to cancer cells emit fluorescence of a first wavelength and the color centers of the nanodiamonds of the second plurality of conjugates attached to healthy cells emit fluorescence of a second wavelength; and wherein the color contrast between the first wavelength and the second wavelength and the location of the respective conjugates delineate a region of cancer cells and a region of healthy cells, respectively. |
priorityDate | 2018-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 143.