http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112458174-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-136 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-178 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7088 |
filingDate | 2020-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-112458174-B |
titleOfInvention | Application of miR-4527in preparation of preparation for diagnosing or treating tumor drug resistance |
abstract | The invention discloses application of miR-4527in preparation of a preparation for diagnosing or treating tumor drug resistance. The invention screens tumor drug-resistant cell strains by a method of continuously increasing the drug action concentration, and finds miRNA with obvious differential expression by detecting the expression quantity of miRNA in the tumor drug-resistant cell strains. The invention discovers that the expression level of miR-4527in drug-resistant tumor cells is remarkably increased, and the inhibition of miR-4527in drug-resistant tumor cells can remarkably reduce the drug resistance of the tumor cells to cis-platinum. |
priorityDate | 2020-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 68.