| abstract |
The invention discloses preparation and application of degradable, biocompatible and high-strength chitin hydrogel. The preparation method comprises the following steps: dropwise adding a cross-linking agent into a chitin solution with the concentration of 5-7% at-10 ℃, stirring for 1-2 h, preparing a gel by a tape casting method, putting into a coagulation bath with the temperature of-10 ℃ and the concentration of 80-100%, physically crosslinking for 6-8 h, and finally washing to obtain the chitin hydrogel. The hydrogel prepared by the invention is degradable, has good biocompatibility and has high mechanical strength. The hydrogel prepared by the invention has great potential in biomedical applications such as bone injury repair, abdominal cavity adhesion prevention, drug delivery and the like. |