http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112441960-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-09 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-09 |
| filingDate | 2020-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112441960-B |
| titleOfInvention | A kind of synthetic method of sulpiride |
| abstract | The present invention provides a method for synthesizing sulpiride. The present invention mixes N-ethyl-2-aminomethylpyrrolidine, ethylene glycol, and 2-methoxy-5-sulfamoyl benzoate methyl ester, and mixes them in a catalyst. The reaction is carried out under the action of sulpiride, the crude sulpiride product is collected after the reaction, and the crude sulpiride product is purified by using a mixed solvent and other substances to obtain a fine sulpiride product. The present invention selects a catalyst suitable for the reaction, which can not only significantly improve the reaction efficiency of sulpiride, reduce the reaction time, but also facilitate recovery, which is beneficial to environmental protection, and more importantly, compared with other catalysts, is more conducive to product yield and Purity improvement. The selected mixed solvent of the present invention is purified, which is more conducive to removing impurities, improving the purity and further improving the yield. The sulpiride refined product prepared by the synthesis method of the present invention has high yield and high purity, is environmentally friendly, and has huge economic benefits. |
| priorityDate | 2020-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 35.