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filingDate 2019-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2021-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-112441952-B
titleOfInvention Cannabidiol-3-sulfonic acid, preparation method and application thereof, and cannabidiol derivative
abstract The invention belongs to the technical field of pharmaceutical chemicals, and particularly relates to cannabidiol-3-sulfonic acid, a preparation method and application thereof, and a cannabidiol derivative. According to the invention, a sulfonic group is introduced into a molecule structure of cannabidiol, the sulfonic group is used as a polar group, so that the polarity of the cannabidiol can be increased, the water solubility of the cannabidiol can be improved, the cannabidiol-3-sulfonic acid can be subjected to a salt forming reaction with inorganic base or organic base, the water solubility of the cannabidiol is further increased, and the druggability of a medicine based on a CBD structure mother nucleus and physiological activity can be increased; in addition, on the premise of ensuring that the basic structure mother nucleus of the cannabidiol is not changed greatly, the sulfonic group newly introduced into the cannabidiol-3-sulfonic acid provided by the invention can be used as a new action site to react with a specific group, so that the research and application range of the cannabidiol-3-sulfonic acid is further widened.
priorityDate 2019-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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