| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d40285e27f4ed83b8728b0d477404958 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2603-98 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C69-33
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-704
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-33
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-704
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate |
2020-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_edccaa40295fbdf1d0ac3f22c74feb68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_77bb152c84cb9d79a020d962dd526399
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9b5ba431fd8699ff3d43f21770f08c24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2164e3b1d6279db061542d9372d39c84
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f8c858ed6b78a3f98f09d74130b0a4e |
| publicationDate |
2021-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-112441924-A |
| titleOfInvention |
Euphorbia joridoides diterpene compound and extraction method and application thereof |
| abstract |
The ingenol compound shown in formula 1 or formula 2 has good safety of compound 1 and 2, and has small cytotoxicity (IC) to different cells 50 >20 mu M), has good safety; when different doses of the compounds 1 and 2 are administered, the effect can be effectively increasedThe inhibition of strong adriamycin on MCF-7/Adr has the reversal multiple of 6.5 to 21.5. The two novel diterpenoids can obviously reverse the drug resistance of drug-resistant tumor cells MCF-7/Adr, enhance the sensitivity of the tumor cells to chemotherapeutic drugs and have better application prospect in anti-tumor multi-drug resistance. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113968837-A |
| priorityDate |
2020-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |