http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112430668-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4bfbab24c3e964ceb3b9630a5fe22d48 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6888 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-686 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-686 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6888 |
| filingDate | 2020-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a53c15e453bfeec5e7116f7f05ccb8e2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5dbeff32c1c40d4eb8769fdce7dc4470 |
| publicationDate | 2021-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112430668-A |
| titleOfInvention | Methods of screening for thyroid hormone signaling disruptors |
| abstract | A method for screening thyroid hormone signal interferers belongs to the field of environmental pollution detection. The method includes exposure experiments on tadpoles of the African clawed frog by exposure of the test substance alone and the combined exposure of the test substance and thyroid hormone T3; Quantitative detection results were analyzed for the effects of the test substance exposure alone and the combined exposure of the test substance and thyroid hormone T3 on the expression of the target gene thibz; when the test substance alone had an effect on the expression of the target gene thibz or when the test substance was combined with thyroid hormone T3 When exposure has an effect on the expression of the target gene thibz induced by thyroid hormone T3, the test substance is determined to be a thyroid hormone signaling disruptor. The invention can quickly detect the TH signal interference effect of the test object, and is suitable for all kinds of chemicals soluble in water. |
| priorityDate | 2020-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 41.