http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112430627-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-88 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-88 |
| filingDate | 2020-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112430627-B |
| titleOfInvention | A method for promoting nucleic acid drug delivery by cationic liposomes by periodic stretching |
| abstract | The invention discloses a method for promoting cationic liposome delivery of nucleic acid drugs through periodic stretching, and belongs to the technical field of medicine. By adding nucleic acid drug-loaded cationic liposomes into the culture medium containing cells, placing the culture medium on the stress loading system to stretch the cells, setting the appropriate stretching length and stretching frequency, and selecting the stretching mode as Adding drug-loaded liposomes for transfection at the same time of continuous 3-8h stretch without space can improve the delivery efficiency of cationic liposomes for nucleic acid drugs. The stretching method used in the invention has more obvious effect on cancer cells, and has the characteristics of easy material acquisition, simple operation, obvious effect, no obvious toxic reaction, etc., and is especially suitable for the current basic laboratory research and clinical departments in my country to carry out various clinical trials. Pre-experiment, with broad market prospects. |
| priorityDate | 2020-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 69.