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filingDate 2020-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-112430334-B
titleOfInvention High-strength shape memory chitosan-based hydrogel and preparation method and application thereof
abstract The invention belongs to the field of biomedical engineering materials, and discloses a high-strength shape memory chitosan-based hydrogel as well as a preparation method and application thereof. The chitosan is dissolved in acetic acid/citric acid solution, then one of dopamine hydrochloride, graphene oxide and dopamine hydrochloride/graphene oxide is added, then the mixture is uniformly stirred, frozen and then thawed by using alkali liquor, and then washed to be neutral by using deionized water and freeze-dried to obtain the high-strength shape memory chitosan-based hydrogel. The high-strength shape memory chitosan-based hydrogel has good mechanical property, does not contain chemical components, has a shape memory function, is fixed into a temporary shape by using ethanol treatment, and can be restored to the original shape again by putting the hydrogel into water, PBS solution or blood, thereby having wide application prospect.
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