http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112426437-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J31-069 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y40-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-549 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6923 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K33-34 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K33-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-69 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82Y40-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82Y5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J31-06 |
| filingDate | 2020-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112426437-B |
| titleOfInvention | DNA functionalized copper oxide nano enzyme and preparation method and application thereof |
| abstract | The invention provides a DNA functionalized copper oxide nanoenzyme and a preparation method and application thereof, the DNA functionalized copper oxide nanoenzyme comprises di-DNA and CuO nanoenzyme, one end of the di-DNA is a DNA sequence consisting of TC bases, the other end of the di-DNA is a DNA sequence consisting of nucleosides, and the di-DNA is adsorbed on the CuO nanoenzyme through the DNA sequence consisting of the TC bases. The DNA functionalized copper oxide nanoenzyme is designed based on the adsorption mechanism of DNA on the surface of the copper oxide nanoenzyme, can be polarized and adsorbed on the surface of the nanoenzyme, and is endowed with a tumor targeting function. The preparation method comprises the following steps: dispersing di-DNA into a buffer solution to obtain a dispersion solution; and mixing the dispersion liquid with CuO nano enzyme and then adsorbing. The preparation method disclosed by the invention is simple to operate, low in cost and mild in reaction conditions, can be used for tumor targeted modification of nano-enzyme, and has a wide application prospect in the fields of disease treatment and the like. |
| priorityDate | 2020-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 32.