http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112415058-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54313 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L3-502707 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5304 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-128 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-416 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-553 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54326 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01L3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-543 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-416 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-553 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-12 |
filingDate | 2020-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-112415058-B |
titleOfInvention | Biosensing detection method based on microchannel resistance change caused by concentration change of insulating microspheres |
abstract | The invention discloses a biosensing detection method based on the change of the concentration of insulating microspheres to cause the change of the resistance of a micro-channel, which is characterized in that biological recognition molecules are respectively modified on the surfaces of magnetic beads and the insulating microspheres, then a target object to be detected is added for biological reaction, after magnetic separation, constant voltage or current is applied to two ends of the micro-channel, the insulating microspheres in reaction liquid pass through the micro-channel under the action of electroosmotic flow and generate obvious blocking effect, thereby causing the change of the resistance of the micro-channel, further causing the current or voltage to change, and the change of the current or voltage is related to the concentration of the insulating microspheres, thus the concentration of the insulating microspheres can be detected according to the principle and the content of the target object to be detected can be indirectly obtained. The invention realizes the detection of a series of target objects, shows good analysis performance, has low equipment cost, is simple and efficient, and has good application prospect in the fields of in-vitro diagnosis, food safety, environmental monitoring and the like. |
priorityDate | 2020-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 37.