http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112410307-B
Outgoing Links
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filingDate | 2020-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-112410307-B |
titleOfInvention | Newcastle disease virus for encoding chicken infectious bursal disease virus VP2Y and application thereof in preparation of biological adjuvant bivalent vaccine |
abstract | The invention discloses a Newcastle disease virus strain for encoding chicken infectious bursal disease virus VP2Y and application thereof in preparation of a biological adjuvant bivalent vaccine. The Newcastle disease recombinant virus provided by the invention is rClone30-VP2Y-chGM-CSF (P/M), rClone30-VP2Y-IRES-chGM-CSF (P/M) or rClone30-VP2Y (NP) -chGM-CSF (P/M); a protein consisting of VP2Y in the recombinant Newcastle disease virus rClone30-VP2Y-chGM-CSF (P/M), rClone30-VP2Y-IRES-chGM-CSF (P/M) or rClone30-VP2Y (NP) -chGM-CSF (P/M), such as amino acid residues 1 to 195 in the sequence 1; wherein the chGM-CSF is a protein consisting of amino acid residues 1-144 from the N terminal of the sequence 3; the Newcastle disease recombinant virus rClone30-VP2Y-chGM-CSF (P/M), rClone30-VP2Y-IRES-chGM-CSF (P/M) or rClone30-VP2Y (NP) -chGM-CSF (P/M) with different sites has the advantages of inducing an organism to generate antibodies 7 days after immunization, enhancing the immune response of the organism and the like, and opens up a new situation on the prevention history of Newcastle disease and infectious bursal disease of chicken. |
priorityDate | 2020-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 262.