http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112410018-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2021-6432 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K11-883 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K11-65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6428 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K11-025 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-02 |
| filingDate | 2020-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112410018-B |
| titleOfInvention | A ratiometric fluorescent probe for visual and quantitative detection of lactate and its application |
| abstract | The invention relates to a ratiometric fluorescent probe for visual and quantitative detection of lactic acid and its application. The preparation method is: preparing bCDs/AgNPs nanocomposites coated with silver nanoparticles and doped with blue fluorescent carbon dots, and the blue fluorescence of bCDs Quenching due to aggregation and doping of AgNPs; combining bCDs/AgNPs nanocomposites with red fluorescence-emitting quantum dots to form bCDs/AgNPs‑rQDs ratiometric fluorescent probes. Lactic acid generates H 2 O 2 under the action of lactate oxidase, and H 2 O 2 etches AgNPs to form silver ions. The structure destruction of the complex restores the blue fluorescence of bCDs, and the formed silver ions can quench the red fluorescence of rQDs. The probe The ratio of the fluorescence intensity (I 445 /I 645 ) changes with the change of the lactic acid concentration, and the change of the ratio of the fluorescence intensity of the probe will cause a significant change in the fluorescence color, thereby realizing visual detection. It is used for the quantitative determination of biomolecules in serum, with high sensitivity and simple detection. |
| priorityDate | 2020-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 52.