http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112402466-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2236-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2236-35 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2236-33 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2236-55 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-11 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D221-22 |
filingDate | 2020-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-112402466-B |
titleOfInvention | Method for separating total alkaloids from huperzia serrata extract |
abstract | The invention relates to a method for separating total alkaloids from a huperzia serrata extract, which comprises the following steps: (1) dissolving; (2) back extraction; (3) decolorizing, filtering, and concentrating; (4) extracting; (5) silica gel chromatography. In the back extraction in the step (2), the extracting solution obtained in the step (1) is back extracted by acid water containing a surfactant, conditions and operations of all steps are optimized and screened, finally, alkaloid from the huperzine serrate is prepared in high yield by a simpler method, and high-purity 6 beta-hydroxy huperzine A, huperzine A and huperzine B are obtained by continuous separation. The method has the advantages of small raw material treatment amount, small solvent consumption, difficult emulsification in the extraction process, short production period, coherent and simple process, strong operability, low production cost, safety and environmental protection, and is suitable for industrial production. |
priorityDate | 2020-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 107.