http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112400109-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8a80b9bef8381cbd855114f4801ba7df |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2030-085 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-462 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D15-363 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D15-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D15-1871 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-08 |
filingDate | 2019-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_afdb4ab07e535616a8eae15a6119f589 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ca0e6f0c9e84a06de74fb4844e20bca5 |
publicationDate | 2021-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-112400109-A |
titleOfInvention | Chromatography system and method for trap-elution mixed mode chromatography |
abstract | In various aspects, the present disclosure relates to methods of materials (eg, kits, column assemblies, liquid chromatography systems, etc.) for performing liquid chromatography employing a first column (eg, a trapping column) and a second column (eg, analytical column). The first column includes a first chromatography material having a first chromatography surface comprising a first hydrophobic surface group and a first ionizable surface group having a first pKa value. The second column includes a second chromatography material having a second chromatography surface comprising a second hydrophobic surface group and (a) a permanently ionized surface group or (b) a second chromatographic surface having a second pKa value Two ionizable surface groups. The hydrophobicity of the first hydrophobic surface group is less than the hydrophobicity of the second hydrophobic surface group. Furthermore, where the second chromatographic surface comprises a second ionizable P surface group, the first pKa value may differ from the second pKa value by 1 to 12 units. |
priorityDate | 2018-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 84.