| abstract |
The invention discloses a method for preparing alpha-aminonitrile, which comprises the following steps: the alpha-aminonitrile is prepared by taking tertiary amine and benzoyl cyanide as reactants and reacting at room temperature through irradiation of visible light in an organic solvent under the condition of oxygen or inert gas. The invention also discloses alpha-amino nitrile and application thereof. The method uses visible light irradiation to promote the tertiary amine and the benzoyl nitrile to react to prepare the alpha-amino nitrile, does not need to additionally add a photocatalyst and a metal catalyst, even does not need to add alkali in certain reactions, and has the advantages of high reaction activity, mild reaction conditions, short reaction time and high yield of target products. The invention uses benzoyl nitrile as cyanation reagent, has low toxicity and low cost, and is beneficial to the industrial production of alpha-amino nitrile. |