http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112386622-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2800-782 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2800-805 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-282 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-9789 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-922 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K127-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-92 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-9789 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61Q19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-282 |
| filingDate | 2020-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112386622-B |
| titleOfInvention | Preparation method and application of freckle-removing active substance |
| abstract | The invention relates to a preparation method and application of an efficient freckle-removing active substance, which is characterized by comprising the following steps: A. drying fresh folium Artemisiae Argyi, adding into round-bottom flask together with deionized water, adjusting pH to 2.0-3.0 with concentrated hydrochloric acid, heating in water bath for extraction, and receiving folium Artemisiae Argyi essential oil with conical flask at liquid outlet of condenser tube; carrying out water bath extraction on the first filter residue under the environment of pH6.5-7.0; extracting the second filter residue in water bath under the environment of pH8.2-8.6; B. mixing the first filtrate, the second filtrate and the third filtrate, and filtering to obtain folium Artemisiae Argyi extract; C. distilling folium Artemisiae Argyi extract under reduced pressure, concentrating to obtain folium Artemisiae Argyi extract, adding appropriate amount of extract into ethanol/ammonium sulfate aqueous two-phase system, adjusting pH to 3-4 with concentrated hydrochloric acid, shaking, and standing; collecting the ethanol phase at the upper layer, and concentrating under reduced pressure to obtain folium Artemisiae Argyi flavonoids; D. mixing the folium artemisiae argyi essential oil and the folium artemisiae argyi flavonoid to obtain the high-efficiency freckle removing active substance. The high-efficiency freckle-removing active substance has a good improvement effect on chloasma. |
| priorityDate | 2020-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 110.