abstract |
Provided are 1,3,5-tris(6-picoline-2-yloxy)benzene targeting the nucleotide-binding oligomerization domain, leucine-rich repeat-containing XI (NLRX1) pathway Derivatives and related compounds. The compounds can be used to treat a variety of conditions, including inflammatory, immune-mediated and/or chronic inflammatory gastrointestinal diseases; systemic immune-mediated diseases; cancer; and infectious diseases. |