http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112384187-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C01P2002-01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C01P2004-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y40-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y30-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C01P2004-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C01P2004-03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C01P2004-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C01P2002-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C01P2006-12 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K6-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K6-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C01B25-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K6-864 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K6-838 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C01B25-327 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K6-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K6-838 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K6-864 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K6-54 |
| filingDate | 2019-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112384187-B |
| titleOfInvention | Stabilized amorphous calcium phosphate doped with fluoride ions and process for producing same |
| abstract | The present invention relates to a process for preparing citrate-coated amorphous calcium phosphate nanoparticles, the process comprising the following steps: 1) providing a first solution of calcium salt and citrate, wherein the molar ratio of citrate ions to calcium ions A ratio ranging from 1 to 2 to obtain a clear first solution; 2) a second solution providing a salt and carbonate capable of giving a phosphate anion; 3) a pH ranging from 8 to 11 mixing the first solution and the second solution together; 4) precipitating the nanoparticles; and 5) drying the nanoparticles obtained from step 4). Preferably and advantageously, the present invention provides in step 2) the addition of a fluoride compound in order to obtain fluorine-doped citrate-coated calcium phosphate nanoparticles or nanoparticle aggregates. The nanoparticles/nanoparticle aggregates of the present invention have specific surface areas and diameters that allow their use as biomaterials for dental applications. |
| priorityDate | 2018-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 80.