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filingDate 2020-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-112379008-B
titleOfInvention A method for detecting the degree of Asp46 racemization of Prx2 protein in erythrocytes
abstract Asp 46 in Prx2 is used as a detection target for early diagnosis of COPD and its kit and application. COPD early diagnosis reagents include the following reagents: cell lysis reagent, anion exchange chromatography column filler, reducing reagent, alkylating reagent, recombinant chymotrypsin reagent, starting buffer, eluent, enzymatic buffer and YPLDF pentapeptide standard product solution. The kit for early detection of chronic obstructive pulmonary disease (COPD) of the present invention can be used to screen patients with early COPD, by detecting the change in the ratio of D/L-Asp 46 in Prx2 in red blood cells, early warning of the occurrence of COPD disease, and for COPD Provides a basis for the diagnosis of the disease. The kit for early detection of chronic obstructive pulmonary disease (COPD) of the invention is easy to use and easy to popularize, and can be applied to clinical diagnosis.
priorityDate 2020-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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