http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112362764-A

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filingDate 2020-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3fd3994d29d89ba7a6da5b9ecd81b7b7
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publicationDate 2021-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-112362764-A
titleOfInvention A magnetic particle modified in situ by silver nanoparticles and its application in the separation and enrichment of β-blockers
abstract The invention discloses a magnetic particle modified by silver nanoparticles in situ and its application in separating and enriching beta-receptor blockers. A preparation method of silver nanoparticle in-situ modified magnetic particles, comprising the steps of: preparing COOH-MNPs magnetic particles by a solvothermal method, and then reacting the COOH-MNPs magnetic particles with a dopa solution to obtain polyDOPA-MNPs modified with polydopa Finally, Ag nanoparticles were in situ modified on the surface of polyDOPA-MNPs magnetic particles to prepare polyDOPA@Ag-MNPs magnetic particles. The in-situ modified magnetic particles of silver nanoparticles (polyDOPA@Ag-MNPs magnetic particles) prepared by the invention can well adsorb and elute β-receptor blockers, and use ESI-MS technology to eluate the eluted magnetic particles. The supernatant was used for detection, which greatly improved the detection sensitivity.
priorityDate 2020-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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