http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112362715-B

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-3278
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N23-2251
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-327
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N23-2251
filingDate 2020-11-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-112362715-B
titleOfInvention A kind of highly sensitive biosensor and its fabrication method and application
abstract The present invention relates to a high-sensitivity biosensor and its manufacturing method and application. First, the nano-gold particles or pine-like gold are modified on the surface of the electrode by electroplating, and then the conductive polymer is modified on the surface of gold materials with different morphologies by electrochemical polymerization, by activating the carboxyl groups on the surface of the conductive polymer; finally The activated electrode is immersed in a specific bioidentifier, and the bioidentifier is immobilized through an amide reaction to obtain the high-sensitivity biosensor. Different biomarkers on highly sensitive biosensors can be used for the specific detection of different biomarkers. The invention uses pine tree-like gold or nano-gold and conductive polymers to prepare high-sensitivity biosensors, greatly increases its surface active area, promotes electron transfer, and enhances the electrical conductivity of electrodes; finally, the sensitivity of the biosensor is improved, and the biological marker is realized. Micro-detection with the lowest detection limit down to aM level (10 ‑9 nM).
priorityDate 2020-11-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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