http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112358442-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-803 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-807 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-803 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-807 |
| filingDate | 2020-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112358442-B |
| titleOfInvention | Preparation method of 2-fluoro-5-formyl chloropyridine |
| abstract | The invention relates to a preparation method of 2-fluoro-5-formyl chloropyridine, belonging to the technical field of organic chemistry. The method comprises the following steps: 1) taking 2-fluoro-5-methylpyridine as a raw material, and reacting in the presence of potassium permanganate or sodium permanganate to obtain 2-fluoro-5-pyridine formate; 2) refluxing 2-fluoro-5-pyridine formate and thionyl chloride or oxalyl chloride in a chlorinated solvent for reaction, distilling the solvent under reduced pressure, adding an alkane solvent, freezing, filtering to obtain a 2-fluoro-5-formyl chloropyridine solution, and rectifying under reduced pressure to obtain the 2-fluoro-5-formyl chloropyridine. The invention has high conversion rate, the purity of the obtained product is up to more than 99.0 percent, the single impurity is less than 0.5 percent, the production cost is low, and the invention is suitable for industrial production. |
| priorityDate | 2020-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 56.