Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8d1993d6dbfbddf08258179e65e2651a |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2015-8518 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-103 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-22 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8509 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6408 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-21084 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 |
filingDate |
2020-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_86eae77c2c2ab51c18f227a0cf61b64b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4cc8d9c49b306ee8e548c1bcbf76ba64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_97ce6f34cc24f4f60ac9faa4e04da1fe http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b97fc54bb87e81f9ac84daf37fd32481 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_119d267a7bc4a5596f2806472fcc7371 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6786da7d964b7bc4ef55c87a948c0c70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bb8e4d827a028a0c3ec59fa678b8d522 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4af001d31f3e3e4451b35edd416e60e8 |
publicationDate |
2021-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-112342240-A |
titleOfInvention |
59R mutant vector for expressing rFC protein and preparation method and application thereof |
abstract |
The invention relates to the technical field of transgenosis, in particular to a vector for expressing rFC protein and a preparation method and application thereof; the vector makes sNT insensitive to pH by mutating an sNT sequence, thereby effectively solving the problem of insolubility caused by fibrosis of foreign protein in a silk gland cavity in a pSG expression system; effectively prevents sNT monomer from forming dimer at low pH; improves the solubility expression capacity and protein activity of the foreign proteins such as rFC mediated by the protein in the pSG bioreactor, is a simple and efficient method for producing the rFC protein, and effectively improves the protection of endangered wild animals. |
priorityDate |
2020-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |