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filingDate 2020-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-112341448-B
titleOfInvention Fluorescent probe and preparation method and application thereof
abstract The invention relates to the technical field of fluorescent probes, in particular to a fluorescent probe for targeted detection of micromolecule mercaptan, a preparation method and application thereof, wherein the structural formula of the fluorescent probe is as follows: the fluorescent probe can realize targeted detection of various micromolecular thiols in cells, and has good selectivity and high detection sensitivity. The fluorescent probe is simple in synthesis method and high in detection speed, does not need long-time incubation in the detection process, and has strong photobleaching resistance; in the detection process, other chemical substances are not required to be added, the operation is simple, the cytotoxicity is low, the intracellular detection is facilitated, the detection limit is low, and the anti-interference capability of other molecules is strong; the operation method is simple, low in cost, universal and easy for large-scale production.
priorityDate 2020-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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