http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112341396-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D241-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-495 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-445 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D241-04 |
filingDate | 2020-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-112341396-B |
titleOfInvention | A novel monoacylglycerol esterase inhibitor and its preparation method and application |
abstract | The invention discloses a novel monoacylglycerol esterase inhibitor and a preparation method and application thereof. Specifically, a class of compounds represented by formula I, or a pharmaceutically acceptable salt thereof, or a stereoisomer thereof, or a deuterated derivative thereof is provided. The experimental results show that the compounds provided by the present invention can effectively inhibit the activity of MAGL, and can be used to prepare MAGL inhibitors, as well as to prevent and/or treat diseases related to abnormal MAGL activity (including endometrial cancer, colorectal cancer, liver cancer, breast cancer, etc.). cancer, ovarian cancer, neurodegenerative diseases, etc.), and has broad application prospects. |
priorityDate | 2020-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 197.