http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112322567-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A40-90 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-93 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P13-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N13-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-01 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-465 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N13-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P13-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-01 |
| filingDate | 2020-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112322567-B |
| titleOfInvention | A mutant strain with acid resistance and high production of ε-polylysine and its application |
| abstract | The invention discloses an acid-resistant and high-yield ε-polylysine mutant strain and an application thereof, belonging to the field of microbial breeding. The present invention obtains a high-yielding strain PL-2-AH66 by performing genetic engineering on Streptomyces and combining with mutation breeding. Compared with the starting strain, the ε-polylysine fermented by the strain at the shake flask level is increased by 150%, and the ε-polylysine production at the level of the 5L fermenter can reach 42.69g/L, and the production intensity is 7.115g/L/d. The high-yielding strain PL-2-AH66 of the present invention has good acid resistance and antibiotic resistance, still has a high survival rate at pH 2.0-3.0, and has good genetic stability. The yield of lysine was basically the same as that of the first passage. The fermentation process of the strain is simple, the process is easy to control, and the yield of ε-polylysine is greatly improved, which lays a solid foundation for the industrial production and application of ε-polylysine. |
| priorityDate | 2020-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 52.