| abstract |
The invention belongs to the technical field of pharmaceutical chemistry, and particularly relates to an aminophenyl ketone compound, and a preparation method and application thereof. The aminophenyl ketone compound provided by the invention has good inhibitory action on PDE4 and better bioavailability, can be applied to the preparation of medicines for treating PDE4 related diseases, and can increase the selectable range of medicines for treating PDE4 related diseases; wherein, part of the aminophenyl ketone compounds have the same effect as positive drugs, and have better development potential. |