http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112316914-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2531-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2533-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2533-80 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/D01F1-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J20-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J20-28021 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J20-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/D01F4-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/D01F8-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/D01F8-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J20-046 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0075 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/D01F1-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J20-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/D01F8-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/D01F8-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J20-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J20-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/D01F4-02 |
| filingDate | 2020-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2023-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2023-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112316914-B |
| titleOfInvention | Silk fibroin micronano fiber microspheres and its preparation method and application |
| abstract | The invention provides a silk fibroin micronano fiber microsphere, a preparation method and application thereof. The present invention uses CaCl 2 /ethanol/H 2 O mixed solution to carry out heat-moisture treatment on silk fibers, and prepares silk fibroin micro-nano fiber suspension through physical-mechanical fiber separation; the prepared silk fibroin micro-nano fiber suspension After being blended with the polysaccharide solution, the cross-linking reaction is carried out, and after electrostatic spraying and freeze-drying treatment, the silk fibroin micronano fiber microspheres are obtained. Through the above method, the present invention can prepare silk fibroin micro-nanofibers while retaining the excellent mechanical properties of silk fibrils, and make them form covalent bonds with polysaccharide molecules under the cross-linking reaction, greatly improving the prepared silk fibrils. The water absorption and morphological stability of nanofibrous microspheres make them have a large specific surface area and rich pore structure, which is conducive to the adhesion and proliferation of cells on the surface of the microspheres. Moreover, the overall preparation process of the microsphere is simple, easy to control, low in cost, and has high application value. |
| priorityDate | 2020-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 54.