| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3662ce5995dada5ea3d9873552592af0 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-76
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-085
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-565
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-52 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-1271
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-085 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 |
| filingDate |
2013-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5fe670db17054f57fb5b5126add87b19
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc2060a5820cc2d56fad7bfe37ce0b03
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d68dadb3b715d791c8cb2f4d57064ba1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_13b1f0a335a90a85b40ea0d92846a805 |
| publicationDate |
2021-02-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-112316135-A |
| titleOfInvention |
Methods of treating Staphylococcus aureus-related diseases |
| abstract |
The present invention provides methods of preventing and/or treating S. aureus-associated bacteremia and sepsis using anti-Staphylococcus aureus alpha-toxin (anti-AT) antibodies, and preventing and/or treating aureus in immunocompromised patients Methods for Staphylococcus aureus-associated pneumonia. Also provided are methods of reducing the bacterial load of Staphylococcus aureus in the bloodstream or heart of a mammalian subject, the methods comprising administering to the subject an effective amount of an isolated anti-Staphylococcus aureus alpha toxin (anti-AT) Antibodies or antigen-binding fragments thereof. Also provided are methods of reducing Staphylococcus aureus bacterial agglutination and/or thromboembolic lesion formation in a mammalian subject, the methods comprising administering to the subject an effective amount of an isolated anti-Staphylococcus aureus alpha toxin (anti-S. AT) antibodies or antigen-binding fragments thereof. Also provided are methods of preventing or reducing the severity of S. aureus-associated pneumonia in an immunocompromised mammalian subject. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114729033-A |
| priorityDate |
2012-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |