http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112300599-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e02801880957b3cc042e3b453d3fd9cc |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1011 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1007 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2001-302 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09B1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N1-30 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09B1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N1-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-06 |
| filingDate | 2020-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_00d893108b45d989fa7447f97c78d6ce http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_12ddf9cfe32f257dc199d64a59e9e75b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9698f48c030d311349fc855061b92a21 |
| publicationDate | 2021-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112300599-A |
| titleOfInvention | A kind of hydrophilic anthracene fluorescent dye and its synthesis method |
| abstract | The invention provides a hydrophilic anthracene fluorescent dye and a synthesis method thereof. The hydrophilicity and stability of anthracene fluorescent dyes were improved by introducing sulfonic acid groups and difluoro substituents. The synthesis method mainly comprises the following steps: the reaction of halogenated benzaldehyde and phenyl Grignard reagent to generate benzyl alcohol derivatives; the oxidation of alcohol hydroxyl groups to ketone carbonyl groups to obtain benzophenone derivatives with phenolic hydroxyl protective groups; the ketone carbonyl groups Converted to dithioketal with ethanedithiol for protection; fluorinated by fluorine reagent to obtain difluorinated anthrones; reacted with lithium reagent to convert to lithium Grignard reagent; oxidized to benzophenone; benzophenone was deprotected base, cyclization reaction under acidic conditions; the obtained fluorinated fluorescent dye is subjected to sulfonation reaction to obtain fluorinated sulfonated fluorescent dye. |
| priorityDate | 2020-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 67.