http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112300188-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P17-181 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-18 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-645 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-18 |
| filingDate | 2020-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112300188-B |
| titleOfInvention | Compounds myrothecin H and I, and preparation method and application thereof |
| abstract | The invention discloses compounds myrothecin H and I, and a preparation method and application thereof. The invention separates myrothecin H and I with anti-tumor activity from the liquid fermentation culture of the Pogostemon cablin endophytic fungus Parastyrtech roridum A697, which are respectively shown as a formula (I) and a formula (II). myrothecin H and I are trichothecene new compounds, and have IC effect on liver cancer cell HepG-2, breast cancer cell MCF-7, glioma cell SF-268 and large cell lung cancer cell NCI-H460 50 The value range is 0.09-9.72 mu M, and the antitumor activity is relatively obvious. The invention provides a candidate drug for researching and developing novel anti-tumor drugs and provides a scientific basis for developing and utilizing the patchouli endophytic fungi resources. |
| priorityDate | 2020-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 36.