http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112293348-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0baff3df9387e5595f3ea64f03b7212d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_03e41fb65cce0c4a0fc6152bd82c542d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d93e21dc3fee2143352e3564915fc364 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2207-30 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-027 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00 |
filingDate | 2019-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2b36cd3e9331ed21133e7b09178e7b33 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_943c15689adfdc338465d960c1846488 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9528b228e58da7073154db43e167e09e |
publicationDate | 2021-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-112293348-A |
titleOfInvention | A method for constructing a mouse model of lumbar disc herniation |
abstract | The invention discloses a method for constructing a mouse model of lumbar intervertebral disc herniation. Intervertebral disc nucleus pulposus tissue; 3) The spinal canal dural sac and nerve root were exposed through the posterior approach, and the degenerated intervertebral disc tissue was placed in the intervertebral foramen area to form nerve root compression to obtain a lumbar disc herniation mouse model; 4) Behavioral testing assesses the presentation and extent of radiating pain in the lower extremities. The invention utilizes the degenerated intervertebral disc tissue to compress the nerve root, which can induce severe and lasting radiating pain symptoms in the lower extremities, and better simulate the chronic course of clinical lumbar disc herniation; Reliable pain behavioral measurement methods and abundant transgenic strains will help to deeply explore the neurobiological mechanism of radiating pain in the lower extremity of lumbar disc herniation. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113274160-A |
priorityDate | 2019-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 26.