http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112285087-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_653c418e41edbb4e1ce8bc5e53e70cec |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y30-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y40-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-658 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82Y40-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82Y30-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82Y15-00 |
| filingDate | 2020-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a55489cd72fcd6c88adcd928b3516736 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f87c65e713dc0299e4f1c006f991efe8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2301459c7d962d4aac8ccf7d5701b6a2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d7c8442cf3fd3cf38f08f5914f9855c9 |
| publicationDate | 2021-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112285087-A |
| titleOfInvention | Preparation of ultrasensitive and high-fidelity SERS sensor based on Au-Se interface and its application in quantitative detection of biological small molecules |
| abstract | The invention relates to the preparation of an ultra-sensitive and high-fidelity SERS sensor based on an Au-Se interface and its application in quantitative detection of biological small molecules, belonging to the field of biological detection and surface-enhanced Raman detection, and is used for high-fidelity detection of biological small molecules in biological systems . Using gold nanoparticles as SERS-enhancing substrates, a high-specificity, high-sensitivity, and high-fidelity SERS sensor based on Au-Se linkage was designed and constructed, which can avoid the interference of biological thiols. It uses boronate as a responsive group and binds to the surface of gold nanoparticles through Au‑Se bonds, and is used to detect endogenous H 2 O 2 in biological systems. Due to the surface plasmon effect, the boronate probe molecule exhibits Very strong Raman signal. Compared with traditional SERS probes based on Au-S bond linkages, high-sensitivity and high-fidelity detection of ultra-low-content molecules in biological samples is achieved, and the method is easily extended to the detection of biologically relevant molecules. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113004887-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113004887-A |
| priorityDate | 2020-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 53.