| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e02801880957b3cc042e3b453d3fd9cc |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08F2438-01 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08F220-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6806 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F220-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6806
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F220-60 |
| filingDate |
2020-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_363bc3019f21f79bfbbe73775eecff40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed5774594a0438afeab624d0193eaf56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_00d893108b45d989fa7447f97c78d6ce
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_12ddf9cfe32f257dc199d64a59e9e75b |
| publicationDate |
2021-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-112280827-A |
| titleOfInvention |
A kind of preparation method of core-shell nucleic acid-immobilized microspheres |
| abstract |
The present invention provides a preparation method of core-shell nucleic acid-immobilized microspheres, which can effectively immobilize nucleic acid molecules. The nucleic acid-immobilized microspheres of the present invention have good singleness, and are favorable for applications in gene sequencing and the like. By connecting initiators or carbon-carbon double bonds on the surface of the microspheres; then in the aqueous phase, the microspheres are polymerized to connect polymer chains containing click chemistry functional groups and azide groups on the surface; and then the nucleic acid is immobilized by click chemistry molecular. The steps are simple and can be applied to common sequencers. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114316132-A |
| priorityDate |
2020-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |