http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112280816-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A20-124 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-06 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-06 |
filingDate | 2020-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-112280816-B |
titleOfInvention | Large-scale preparation method of marine source type I collagen subunit |
abstract | The invention discloses a large-scale preparation method of marine source type I collagen subunit, which takes marine organism processing by-products as raw materials, and utilizes acetic acid extraction and salting-out electrodialysis purification integrated technology to prepare type I collagen; taking I-type collagen as a raw material, and preparing a mixed solution of subunit alpha 1 and alpha 2 of the I-type collagen by utilizing a collagenase enzymolysis synergistic multi-stage membrane separation linkage technology; on the basis, the type I collagen subunits alpha 1 and alpha 2 are prepared by using salting out in combination with an electrodialysis technology. Aiming at the technical bottleneck that the existing preparation process of the collagen subunits can only prepare milligram-level and microgram-level samples and cannot realize large-scale production, the invention constructs a technical system integrating a collagenase enzymolysis synergistic multi-level membrane separation linkage technology and a salting-out synergistic electrodialysis technology, and prepares the type I collagen subunits alpha 1 and alpha 2 in a large scale. |
priorityDate | 2020-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 552.