abstract |
The present invention provides a class of deuterated alkene aminocarbonyl compounds and a preparation method and application thereof. Specifically, a compound of formula (I), or an enantiomer or diastereomer or a mixture thereof, or a salt thereof, wherein X is halogen or undeuterated or one or more deuterated or per-deuterated C 1 -C 6 haloalkyl; R 1 is undeuterated or one or more deuterated or per-deuterated C 1 -C 6 haloalkyl, or undeuterated or once or Multiple deuterated or perdeuterated C 2 -C 6 haloalkenyl; R 2 is hydrogen, deuterium or halogen, Y is O, S, NR 10 or CR 11 R 12 ; R 3 , R 4 , R 5 , R 6 , R 7 , R 8 , R 9 , R 10 , R 11 and R 12 are each independently selected from: hydrogen or deuterium; with the proviso that at least one of R 1 , R 3 or R 4 is deuterated or deuterium. |