http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112279801-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D223-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-72 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D223-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-72 |
filingDate | 2020-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-112279801-B |
titleOfInvention | Synthetic method of 3-methylsulfonyl substituted nitrogen heterocyclic compound |
abstract | The invention discloses a synthesis method of a 3-methylsulfonyl substituted nitrogen heterocyclic compound, belonging to the technical field of organic synthesis. The technical scheme provided by the invention has the key points that: dissolving a saturated cyclic amine compound, pyrosulfite and peroxide containing methyl in a solvent, adding a catalyst and alkali into a reaction system, and reacting at the temperature of 100-140 ℃ in an air atmosphere to obtain a target product, namely the 3-methylsulfonyl substituted nitrogen heterocyclic compound. The method synthesizes the target product 3-methylsulfonyl substituted nitrogen heterocyclic compound by carrying out one-pot multi-component series reaction on the easily obtained saturated cyclic amine compound, the pyrosulfite and the methyl peroxide compound, has the advantages of simple and convenient operation, mild condition, wide substrate application range and the like, and is suitable for industrial production. |
priorityDate | 2020-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 52.