http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112274655-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y40-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6935 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82Y5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82Y40-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-69 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-08 |
| filingDate | 2020-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2023-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2023-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112274655-B |
| titleOfInvention | A nano drug-loaded particle with polycitrate as a carrier and its preparation method and application |
| abstract | The invention relates to the field of polymer pharmaceutical preparations, in particular to a nano drug-loaded particle with polycitric acid as a carrier, a preparation method and application thereof. The nano drug-loaded particles disclosed in the present invention are prepared by carrying hydrophobic drugs on PCM as a carrier, as follows: respectively dissolving PCM and hydrophobic drugs in organic solvents, and then the organic phase containing PCM and hydrophobic drugs is ultrasonically Or drop into the water phase under stirring conditions, and finally use dialysis to remove the organic solvent to obtain nanometer drug-loaded particles. The nano drug-loaded particles disclosed by the present invention not only have a simple preparation process, but also have a high drug-loading capacity and a good sustained-release effect; tests have shown that the PCMNPs can not only improve the anti-tumor effect of drugs, but also improve the tumor inhibition rate, and the PCMNPs It can increase the weight of mice, reduce the toxic and side effects of drugs, and has great market application and promotion prospects. |
| priorityDate | 2020-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 39.