http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112255347-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_85a7dbbfe7f01a0f6454543b93101151 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-02 |
| filingDate | 2020-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dccfa86687d46b9378ecd6ef61c37712 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0c3fef3ce2f99ac2cffde4a65b4028a7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_58bd74ac007238f1528cac8594e2d17d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_533df99b09bfddc715a96a01a821772a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_11aa725dea278cd01c2b15cdcd255a88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ef9bee421a9eadf4eb5fe81916d78631 |
| publicationDate | 2021-01-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112255347-A |
| titleOfInvention | A kind of determination method of pyrimethamine isomer |
| abstract | The invention discloses a method for measuring pyrimethamine isomers. First, a pyrimethamine isomer standard sample solution and a pyrimethamine sample solution are prepared; then liquid chromatography is used to continuously measure the standard sample solution for several times. Calculate the response value of pyrimethamine isomers in each measurement, until the relative change of the two adjacent response values is less than 1.5%, according to the following chromatographic conditions, the standard solution and the sample solution were measured for multiple times, and the standard solution was obtained. The chromatograms of the sample solution and the sample solution were obtained; finally, the mass fraction of pyrimethamine isomers in the sample solution was calculated according to formula (1). The standard deviation of the assay method of the invention is 0.24, the coefficient of variation is 0.25%, the average recovery rate is 99.3%, and the linear correlation coefficient is 0.991, the pyrimethamine isomers can be completely separated from the pyrimethamine, and the chromatographic peak shape is good. The integral calculation results are accurate and repeatable, and the obtained results have high reliability. |
| priorityDate | 2020-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 36.