| abstract |
The invention relates to a caper drug-loaded nanofiber membrane, a preparation method and application thereof, and belongs to the field of drug-loaded nanofiber preparation. A caper drug-loaded nanofiber membrane is obtained by electrospinning a spinning solution obtained by mixing a polylactic acid solution and a caper ethyl acetate extract. The caper ethyl acetate extract is prepared by the following method: using absolute ethanol to reflux and purify caper fruit powder in a water bath at 60°C; collecting the supernatant after filtration, and using the obtained supernatant with water After dilution, use an equal volume of petroleum ether for several extractions, add sodium chloride during the extraction process, the solution is divided into three layers, take the bottom layer solution and continue to add an equal volume of ethyl acetate for extraction, after the solution is layered, take the lower layer solution and concentrate. , the caper ethyl acetate extract was obtained. The fiber membrane of the present invention has antibacterial properties, good hydrophilicity and good moisture permeability. |