http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112251454-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2795-10122 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-2434 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y302-01092 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-162 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-47 |
| filingDate | 2020-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2023-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2023-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112251454-B |
| titleOfInvention | An anti-Salmonella phage-expressed endolysin and perforin composition and its preparation method and application |
| abstract | The invention provides an anti-Salmonella phage-expressed endolysin and perforin composition, a preparation method and application thereof, and belongs to the technical field of bioengineering. The amino acid sequence of the endolysin is shown in SEQ ID NO:1, and the amino acid sequence of the perforin is shown in SEQ ID NO:2. The endolysin Lys 2 and perforin Hol 2 expressed by the phage of the present invention have broad-spectrum bactericidal activity, have good antibacterial effects on various Gram-positive and Gram-negative bacteria, and have obvious antibacterial effects on Salmonella endolysin Lys 2 has an N-terminal enzymatic domain that can cleave β-1,4-glycosidic bonds, and perforin Hol 2 has a conserved domain that can destroy cells and transmit information to control The cell lysis time can be used in the preparation of drugs for preventing, inhibiting or treating cell infection, and has popularization and application value in the fields of medical treatment and food safety. |
| priorityDate | 2020-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 393.