http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112250700-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1055 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6486 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F5-022 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09B57-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09B57-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F5-02 |
filingDate | 2020-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-112250700-B |
titleOfInvention | BODIPY (boron dipyrromethene) protein misfolding probe Halo-BODIPY as well as preparation method and application thereof |
abstract | The invention discloses a BODIPY (boron dipyrromethene protein misfolding probe), a preparation method and application thereof. The small molecular fluorescent probe is prepared by utilizing Halo linker and BODIPY through organic synthesis reaction, can realize effective identification of misfolded and aggregated proteins, and has low cytotoxicity, good biocompatibility and stable fluorescence property because the probe Halo-BODIPY is designed based on a luminescent mother nucleus of the BODIPY; the molecular absorption coefficient is large, the background interference resistance is strong, the fluorescence quantum yield is high, and the probe can be used as an excellent probe design platform and has extremely important application in the fields of biological imaging, fluorescence labeling, biosensors, drug research and development and the like. |
priorityDate | 2020-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 66.