http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112250533-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2231-645 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C315-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J31-0245 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B53-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-90 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C315-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C317-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J31-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B53-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-90 |
| filingDate | 2020-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-112250533-B |
| titleOfInvention | Synthesis method of (S) -1- (3-ethoxy-4-methoxyphenyl) -2- (methylsulfonyl) ethylamine |
| abstract | The invention relates to a synthesis method of (S) -1- (3-ethoxy-4-methoxyphenyl) -2- (methylsulfonyl) ethylamine. The method comprises the following steps: mixing 1- (3-ethoxy-4-methoxyphenyl) -2- (methylsulfonyl) vinylamine, a chiral catalyst, an acid and a solvent for reaction; the structural formula of the chiral catalyst is shown as a formula (I), and R is selected from hydrogen atom, alkyl, aromatic ring, alkoxy, halogen atom, amino, cyano, hydroxyl, trifluoromethyl, nitro, ester group or amide group. Can generate (S) -1- (3-ethoxy-4-methoxyphenyl) -2- (methylsulfonyl) ethylamine with high chiral purity in one step, and simultaneously, the product is easy to separate and purify and has high yield. In addition, the method has the advantages of mild reaction conditions, stable process, simple, convenient and safe reaction operation, low production cost, simple and feasible three-waste treatment, environmental friendliness, easily obtained raw materials and low production cost, and is suitable for industrial production. |
| priorityDate | 2020-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 86.