| abstract |
The present invention relates to a pharmaceutical preparation of tetrahydroisoquinoline derivatives and a preparation method thereof. The tetrahydroisoquinoline derivatives have a structure as shown in formula I: Wherein, R 1 is a substituted or unsubstituted aromatic ring or aromatic heterocyclic ring, Represents one of cyclohexylamino, 4-methyl-1,4-diazepan-1-yl, and 3-oxo-1,4-diazepan-1-yl. The pharmaceutical preparation of tetrahydroisoquinoline derivatives consists of tetrahydroisoquinoline derivatives, fillers, disintegrants, binders, lubricants and auxiliary agents. The tetrahydroisoquinoline derivative pharmaceutical preparation has good dissolution rate and high stability. |