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filingDate 2019-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-112239768-B
titleOfInvention A method of delivering exogenous molecules into T cells
abstract The present invention relates to a method for delivering exogenous molecules into T cells. The method comprises mixing T cells and reagents containing exogenous molecules, dripping the obtained cell suspension onto the surface of a photothermal substrate, and irradiating the cells with a laser light source in the near-infrared band. The method has strong versatility, high transfer efficiency and transfection efficiency, low cytotoxicity, high harvest rate of transformed cells, and large one-time cell processing throughput. The killing efficiency of the CAR-T cells prepared by the present invention to tumor cells can be as high as 95%.
priorityDate 2019-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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