http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112236535-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e93e80d9739a9f8458613ea22889ae43 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-112 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-118 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6827 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6886 |
filingDate | 2019-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c280ad87150a6e1c00c3986c903715bd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_27eedbf06b12e7845e93cbb81c836c76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b34af78a639b4c1ae08f4da44a590de7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_42fd023aeb05d2dc3b2976c865dd33b1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c2c5ead0d5bf7e3e82355f06cf1d32d7 |
publicationDate | 2021-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-112236535-A |
titleOfInvention | Method for cancer detection and monitoring by means of personalized detection of circulating tumor DNA |
abstract | The present invention provides methods for detecting single nucleotide variants in breast, bladder or colorectal cancer. Other methods and compositions are provided, such as reaction mixtures and solid supports comprising clonal populations of nucleic acids. For example, provided herein are methods for monitoring and detecting early recurrence or metastasis of breast, bladder or colorectal cancer, comprising generating a set of amplicons by performing a multiplex amplification reaction on nucleic acids isolated from a blood or urine sample or portion thereof from a patient who has received treatment for breast, bladder or colorectal cancer, wherein each amplicon in the set of amplicons spans at least one single nucleotide variant locus in a set of patient-specific single nucleotide variant loci associated with breast, bladder or colorectal cancer; and determining the sequence of at least one segment of each amplicon in the set of amplicons, the at least one segment comprising a patient-specific single nucleotide variant locus, wherein detection of one or more patient-specific single nucleotide variants is indicative of early recurrence or metastasis of breast cancer, bladder cancer, or colorectal cancer. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114574576-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114574576-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113718033-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113539355-A |
priorityDate | 2018-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 975.